body:has(.article-page){background:var(--paper)}.article-page{--ap-paper:var(--paper);--ap-surface:var(--card);--ap-ink:var(--ink);--ap-ink-2:var(--ink-2);--ap-muted:var(--muted);--ap-hair:var(--hair);--ap-hair-2:var(--hair-2);--ap-accent:var(--accent);--ap-accent-dk:var(--accent-dk);--ap-accent-lt:var(--accent-lt);--reading-max:800px;--rail-w:248px;--rail-gap:24px;--shell-max:calc(var(--reading-max) + 2 * (var(--rail-gap) + var(--rail-w)))}.article-shell{max-width:var(--shell-max);margin:0 auto;padding:0 24px;display:grid;grid-template-columns:minmax(0,var(--rail-w)) minmax(0,var(--reading-max)) minmax(0,var(--rail-w));gap:var(--rail-gap);justify-content:center;align-items:start}.article-shell.is-ready{transition:grid-template-columns var(--dur-slow) var(--ease-standard)}.article-body{margin-top:2rem;padding-bottom:5rem}.article-hero{background:linear-gradient(180deg,var(--art-hero-grad) 0,var(--paper) 100%);border-bottom:1px solid var(--hair);padding:1.75rem 0 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var(--accent-bd);font-family:var(--font-inter,sans-serif);font-size:13px;font-style:normal;line-height:1.55;color:var(--ink-2)}.entity-content .marginalia>:last-child{margin-bottom:0}@media (max-width:720px){.entity-content .marginalia{float:none;width:auto;margin:1.2rem 0}}.entity-content ol,.entity-content ul{margin:.4rem 0 1.2rem;padding-left:1.45rem}.entity-content li{margin-bottom:.45rem}.entity-content ul>li{list-style:none;position:relative}.entity-content ul>li:before{content:"";position:absolute;left:-1.05rem;top:.66em;width:6px;height:6px;border-radius:50%;background:var(--accent);opacity:.5}.entity-content ol{list-style:none;counter-reset:ol}.entity-content ol>li{counter-increment:ol;position:relative}.entity-content ol>li:before{content:counter(ol) ".";position:absolute;left:-1.5rem;top:.04em;font-family:var(--font-mono,monospace);font-size:12px;font-weight:600;color:var(--accent)}.entity-content li>ol,.entity-content li>ul{margin:.45rem 0 .3rem}.entity-content strong{font-weight:700;color:var(--ink)}.entity-content em{font-style:italic}.entity-content a{color:var(--accent-dk);text-decoration:underline;text-decoration-color:var(--accent-bd);text-decoration-thickness:1.5px;text-underline-offset:3px;transition:color var(--dur-fast),text-decoration-color var(--dur-fast)}.entity-content a:hover{color:var(--accent);text-decoration-color:var(--accent)}.entity-content hr{display:none}.entity-content .inline-code,.entity-content code{font-family:var(--font-mono,monospace);font-size:.82em;background:var(--paper-2);border:1px solid var(--hair);border-radius:5px;padding:.08em .4em;color:var(--ink)}.entity-content pre.code-block{margin:1.4rem 0 1.6rem;padding:14px 16px;background:var(--art-code-bg);border:1px solid var(--art-code-bd);border-radius:12px;overflow-x:auto;font-size:13.5px;line-height:1.6;-webkit-overflow-scrolling:touch}.entity-content pre.code-block code{background:none;border:none;border-radius:0;padding:0;font-size:inherit;color:var(--prose-table);white-space:pre}.entity-content .mermaid-diagram{margin:1.8rem 0;padding:1.4rem 1rem;background:var(--art-frame-bg);border:1px solid var(--art-frame-bd);border-radius:14px;text-align:center;overflow-x:auto;-webkit-overflow-scrolling:touch}.entity-content .mermaid-diagram svg{max-width:100%;height:auto}.entity-content .algo-card{margin:1.8rem 0;background:var(--art-frame-bg);border:1px solid var(--art-frame-bd);border-radius:var(--radius-lg,14px);overflow:hidden}.entity-content .algo-head{display:flex;align-items:center;gap:10px;padding:12px 18px;background:var(--accent)}.algo-head-ic{flex-shrink:0;width:24px;height:24px;display:flex;align-items:center;justify-content:center;border:1.5px solid color-mix(in srgb,var(--on-accent) 75%,transparent);border-radius:50%;color:var(--on-accent)}.algo-head-title{font-family:var(--font-inter,sans-serif);font-size:12.5px;font-weight:700;letter-spacing:.05em;text-transform:uppercase;color:var(--on-accent)}.entity-content .algo-steps{list-style:none;margin:0;padding:20px 20px 22px;counter-reset:none}.entity-content .algo-step{position:relative;display:flex;gap:14px;padding-bottom:20px}.entity-content .algo-step:last-child{padding-bottom:0}.entity-content .algo-step:not(:last-child):before{content:"";position:absolute;left:13px;top:28px;bottom:0;width:1px;background:repeating-linear-gradient(to bottom,var(--accent-lt-2) 0,var(--accent-lt-2) 3px,transparent 3px,transparent 7px)}.algo-num{flex-shrink:0;width:27px;height:27px;display:flex;align-items:center;justify-content:center;font-family:var(--font-inter,sans-serif);font-size:12.5px;font-weight:700;color:var(--accent-dk);background:var(--accent-lt);border-radius:50%;z-index:1}.algo-step-body{min-width:0;padding-top:3px}.entity-content .algo-step-text{margin:0;font-family:var(--font-inter,sans-serif);font-size:14.5px;line-height:1.55;color:var(--ink)}.algo-step-text strong{color:var(--ink)}.entity-content .algo-branches{list-style:none;margin:10px 0 0;padding:2px 0 2px 14px;border-left:2px solid var(--hair-2);display:flex;flex-direction:column;gap:6px}.algo-branch{display:flex;flex-wrap:wrap;align-items:baseline;gap:6px;font-family:var(--font-inter,sans-serif);font-size:13.5px;line-height:1.5;color:var(--muted)}.algo-branch-cond{color:var(--ink-2);font-weight:600}.algo-branch-arrow{color:var(--accent)}.algo-branch-action{color:var(--muted)}.entity-content .article-figure{display:flex;flex-direction:column;align-items:center;justify-content:center;width:100%;margin:1.8rem 0;padding:14px 14px 10px;background:var(--art-frame-bg);border:1px solid var(--art-frame-bd);border-radius:14px;font-family:inherit;text-align:center;cursor:zoom-in}.entity-content .article-figure img{display:block;max-width:100%;width:auto;height:auto;max-height:min(52vh,480px);-o-object-fit:contain;object-fit:contain;border-radius:8px;background:var(--art-frame-bg)}.entity-content .article-figcaption{display:block;margin-top:.6rem;font-family:var(--font-inter,sans-serif);font-size:13px;line-height:1.5;color:var(--prose-caption);counter-increment:figure}.entity-content .article-figcaption:before{content:"Рис. 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" counter(table);display:block;margin-bottom:.45rem;font-family:var(--font-mono,monospace);font-size:11px;font-weight:600;letter-spacing:.07em;text-transform:uppercase;color:var(--muted)}.entity-content .table-wrap{position:relative;overflow-x:auto;margin:1.4rem 0 1.6rem;border:1px solid var(--hair);border-radius:12px;-webkit-overflow-scrolling:touch}.entity-content .table-figure .table-wrap{margin:0}.entity-content table{width:100%;table-layout:auto;border-collapse:collapse;font-family:var(--font-inter,sans-serif);font-size:14px;font-variant-numeric:tabular-nums}.entity-content th{background:var(--accent-lt);font-weight:600;text-align:left;font-size:12.5px;color:var(--accent-dk);border-bottom:1px solid var(--accent-bd)}.entity-content td,.entity-content th{padding:10px 14px;overflow-wrap:break-word}.entity-content td{border-bottom:1px solid var(--paper-2);vertical-align:top;color:var(--prose-table);line-height:1.55}.entity-content td,.entity-content th{min-width:4.5rem}@media (max-width:640px){.entity-content table{font-size:12.5px}.entity-content td,.entity-content th{padding:7px 9px}}.entity-content tr:last-child td{border-bottom:none}.entity-content tbody tr:nth-child(2n) td{background:var(--art-row-even)}.entity-content tbody td:first-child{font-weight:600;color:var(--ink)}.entity-content tbody tr:hover td{background:color-mix(in srgb,var(--accent) 7%,transparent)}.entity-content .tb-head{display:flex;align-items:baseline;justify-content:space-between;gap:10px;flex-wrap:wrap;margin-bottom:.5rem}.entity-content .tb-title{font-weight:650;font-size:14px;color:var(--ink)}.entity-content .tb-search{display:inline-flex;align-items:center;gap:6px;padding:3px 10px;border:1px solid var(--hair);border-radius:999px;color:var(--muted)}.entity-content .tb-search input{border:none;outline:none;background:transparent;font-size:12.5px;color:var(--ink);width:150px;font-family:inherit}.entity-content .tb-sort{display:inline-flex;align-items:baseline;gap:4px;border:none;background:none;padding:0;font:inherit;color:inherit;cursor:pointer;text-align:left}.entity-content .tb-unit{font-weight:400;opacity:.75}.entity-content .tb-sort-ic{flex-shrink:0;align-self:center;opacity:.45}.entity-content .tb-sort-ic.active{opacity:1}.entity-content .tb-empty{margin:0;padding:14px;text-align:center;font-size:13px;color:var(--muted)}.entity-content .tb-caption{margin-top:.5rem;font-size:12.5px;color:var(--muted)}.entity-content .callout{display:flex;gap:12px;align-items:flex-start;margin:1.4rem 0;padding:14px 16px;background:var(--art-callout-bg);border:1px solid var(--art-callout-bd);border-left:3px solid var(--accent);border-radius:10px}.callout-ic{flex-shrink:0;margin-top:1px;width:22px;height:22px;display:flex;align-items:center;justify-content:center;color:var(--accent)}.callout-body{min-width:0;font-family:var(--font-inter,sans-serif);font-size:14px;line-height:1.6;color:var(--prose-table)}.callout-body>:last-child{margin-bottom:0}.callout-body p{margin-bottom:.5rem}.entity-content .callout--info{background:var(--info-bg);border-color:var(--info-bd);border-left-color:var(--info)}.callout--info .callout-ic{color:var(--info)}.entity-content .callout--tip{background:var(--success-bg);border-color:var(--success-bd);border-left-color:var(--success)}.callout--tip .callout-ic{color:var(--success)}.entity-content .callout--warn{background:var(--warn-bg);border-color:var(--warn-bd);border-left-color:var(--warn)}.callout--warn .callout-ic{color:var(--warn)}.entity-content .callout--danger{background:var(--clinical-bg);border-color:var(--clinical-bd);border-left-color:var(--clinical);border-left-width:4px}.callout--danger .callout-ic{color:var(--clinical)}.callout--danger .callout-body{color:var(--prose-danger)}.callout--danger .callout-body strong{color:var(--clinical)}.callout--danger .callout-body a{color:var(--clinical);text-decoration-color:var(--clinical-bd)}.callout--danger .callout-body a:hover{text-decoration-color:var(--clinical)}.entity-content .rx-flag{background:var(--clinical-bg);color:var(--clinical);font-weight:600;padding:0 .28em;border-radius:4px;box-decoration-break:clone;-webkit-box-decoration-break:clone}.entity-content .callout--quote{background:transparent;border:none;border-left:3px solid var(--hair-2);border-radius:0;padding:2px 0 2px 16px}.callout--quote .callout-ic{color:var(--muted)}.callout--quote .callout-body{font-style:italic;color:var(--prose-quote)}.entity-content .table-wrap.clinical{border-left:3px solid var(--clinical)}.entity-content .table-wrap.clinical th{color:var(--clinical)}.article-rail .sidebar-card{background:var(--card);border-color:var(--hair);border-radius:14px;padding:1rem 1.05rem}.article-rail .sidebar-label{color:var(--muted)}.sidebar-toggle-row{display:none}.sidebar-toggle{display:inline-flex;align-items:center;gap:8px;width:-moz-fit-content;width:fit-content;max-width:100%;padding:8px 14px 8px 10px;background:var(--card);border:1px solid var(--accent-bd);border-radius:100px;color:var(--accent-dk);cursor:pointer;box-shadow:var(--shadow);transition:background var(--dur-fast) var(--ease-out),border-color var(--dur-fast) var(--ease-out),color var(--dur-fast) var(--ease-out),box-shadow var(--dur-fast) var(--ease-out);font-family:inherit;font-size:12.5px;font-weight:600;letter-spacing:.01em;line-height:1;-webkit-tap-highlight-color:transparent}.sidebar-toggle:hover{border-color:var(--accent);box-shadow:var(--shadow-float)}.sidebar-toggle:active,.sidebar-toggle:hover{background:var(--accent-lt)}.sidebar-toggle:focus-visible{outline:none;box-shadow:0 0 0 3px var(--focus-ring),var(--shadow)}.sidebar-toggle-icon{display:flex;align-items:center;justify-content:center;width:24px;height:24px;flex-shrink:0}.sidebar-toggle-label{white-space:nowrap;overflow:hidden;text-overflow:ellipsis;max-width:120px}.rail-toc-wrapper{overflow-x:hidden;display:flex;flex-direction:column;gap:14px;padding-bottom:1rem}.sidebar-backdrop{position:fixed;inset:0;z-index:49;background:rgba(22,33,28,.35);backdrop-filter:blur(2px);-webkit-backdrop-filter:blur(2px);opacity:0;pointer-events:none;transition:opacity var(--dur-slow)}@media (min-width:1101px){.sidebar-backdrop{display:none}}@media 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(max-width:640px){.row-2{grid-template-columns:1fr}}.disc-more{margin-top:1.1rem;display:flex;justify-content:center}.btn-ghost{display:inline-flex;align-items:center;gap:7px;font-size:14px;font-weight:600;color:var(--accent-dk);text-decoration:none;padding:9px 18px;border:1px solid var(--hair-2);border-radius:12px;background:var(--card);transition:border-color var(--dur-quick),background var(--dur-quick),transform var(--dur-quick)}.btn-ghost:hover{border-color:var(--accent-bd);background:var(--accent-lt);transform:translateY(-1px)}.btn-ghost svg{transition:transform var(--dur-base) var(--ease-spring)}.btn-ghost:hover svg{transform:translateX(3px)}.conn-pair{display:flex;align-items:center;gap:10px;flex-wrap:wrap;background:var(--card);border:1px solid var(--hair);border-radius:12px;padding:12px 14px;transition:border-color var(--dur-quick),box-shadow var(--dur-quick)}.conn-pair:hover{border-color:var(--hair-2);box-shadow:0 8px 20px -10px rgba(16,40,32,.16)}.conn-rel{font-family:var(--font-mono,monospace);font-size:11px;color:var(--muted);white-space:nowrap}.search-suggest{animation:suggestIn .18s var(--ease-spring)}@keyframes suggestIn{0%{opacity:0;transform:translateY(-6px)}to{opacity:1;transform:none}}@media (prefers-reduced-motion:reduce){.btn-ghost:hover svg,.disc-card:hover .disc-ic{transform:none}.search-suggest{animation:none}}.disc-card:active{transform:scale(.985)}.conn-list{display:flex;flex-direction:column;gap:10px;margin-top:18px}@media (prefers-reduced-motion:reduce){.home-hero.rise>*,.stagger>*{animation:none}.disc-card:active{transform:none}}.hero-constellation{position:relative;display:grid;place-items:center;min-height:clamp(640px,80vh,820px);margin-top:6px}.hc-svg{position:absolute;inset:0;width:100%;height:100%;pointer-events:none;overflow:visible}.cnode{pointer-events:auto;cursor:pointer}.cnode-spoke{transition:stroke-opacity var(--dur-base)}.cnode:focus-visible .cnode-spoke,.cnode:hover .cnode-spoke{stroke-opacity:.5}.cnode-floaty{transform-box:fill-box;animation:hcFloat var(--dur,7s) ease-in-out var(--delay,0s) infinite alternate}@keyframes hcFloat{0%{transform:translate(0)}to{transform:translate(-7px,5px)}}.cnode-scale{transform-box:fill-box;transform-origin:center;transition:transform var(--dur-base) var(--ease-spring)}.cnode:focus-visible .cnode-scale,.cnode:hover .cnode-scale{transform:scale(1.12)}.cnode circle{transition:stroke-width var(--dur-base)}.cnode:focus-visible circle,.cnode:hover circle{stroke-width:2.6px}.cnode:focus-visible{outline:none}.cnode:focus-visible circle{stroke:var(--ink)}.cnode-count{font-family:var(--font-mono,monospace);font-size:17px;font-weight:600}.cnode-label{font-family:var(--font-inter,sans-serif);font-size:14px;font-weight:600;fill:var(--ink-2)}.cnode:focus-visible .cnode-label,.cnode:hover .cnode-label{fill:var(--ink)}.hc-center{position:relative;z-index:2;text-align:center;max-width:560px;padding:0 16px}.hc-center:before{content:"";position:absolute;inset:-54px -44px;background:radial-gradient(ellipse at center,var(--paper) 40%,transparent 76%);z-index:-1}.hc-title{font-family:var(--font-display,sans-serif);font-size:clamp(30px,4.8vw,50px);font-weight:700;letter-spacing:-.035em;line-height:1.06;color:var(--ink);text-wrap:balance}.hc-title .accent{color:var(--accent)}.hc-lede{font-size:clamp(14px,1.4vw,16px);color:var(--ink-2);margin:12px auto 0;max-width:42ch;line-height:1.5}.hc-search{margin-top:1.4rem}.hc-meta{margin-top:1rem;font-family:var(--font-mono,monospace);font-size:11.5px;color:var(--muted)}.hc-meta kbd{font-family:inherit;border:1px solid var(--hair-2);border-radius:5px;padding:1px 6px;color:var(--ink-2)}@media (max-width:720px){.hc-svg{display:none}.hero-constellation{min-height:auto;padding:clamp(40px,9vw,72px) 0 clamp(28px,6vw,44px)}.hc-lede{max-width:34ch}}@media (prefers-reduced-motion:reduce){.cnode-floaty{animation:none}.cnode-scale{transition:none}}.field select.prof-select{width:100%;border:1.5px solid var(--hair-2);border-radius:10px;padding:10px 13px;font-family:inherit;font-size:14px;color:var(--ink);background:var(--card);outline:none;cursor:pointer;transition:border-color var(--dur-fast),box-shadow var(--dur-fast)}.field select.prof-select:focus{border-color:var(--accent);box-shadow:0 0 0 3px var(--focus-ring)}.prof-ok{color:var(--accent-dk);background:var(--accent-lt);border:1px solid var(--accent-bd);border-radius:8px}.prof-err,.prof-ok{font-size:12.5px;padding:7px 11px;margin-bottom:12px}.prof-err{color:var(--danger);background:var(--danger-bg);border:1px solid var(--danger-bd);border-radius:8px}.logout-row{display:flex;align-items:center;justify-content:space-between;gap:12px;flex-wrap:wrap}.btn-danger{display:inline-flex;align-items:center;gap:8px;background:var(--on-accent);color:var(--danger);border:1.5px solid var(--danger-bd);border-radius:10px;padding:10px 18px;font-size:14px;font-weight:600;font-family:inherit;cursor:pointer;transition:background var(--dur-fast),border-color var(--dur-fast)}.btn-danger:hover{background:var(--danger-bg);border-color:var(--danger-bd)}.btn-danger:disabled{opacity:.6;cursor:not-allowed}